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The Effects of 5-Aza-2′- Deoxycytidine and Trichostatin A on Gene Expression and DNA Methylation Status in Cloned Bovine Blastocysts

We previously found that treatment of both donor cells and early cloned embryos with combination of 5-aza-2′-deoxycytidine (5-aza-dC) and trichostatin A (TSA) significantly improve the in vitro and full-term development of nuclear transfer (NT) bovine embryos. To investigate how this treatment impro...

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Detalhes bibliográficos
Main Authors: Wang, Yongsheng, Su, Jianmin, Wang, Lijun, Xu, Wenbing, Quan, Fusheng, Liu, Jun, Zhang, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146745/
https://ncbi.nlm.nih.gov/pubmed/21486115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2010.0098
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