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Anti-DNA:RNA Antibodies and Silicon Photonic Microring Resonator Arrays Enable the Ultrasensitive, Multiplexed Detection of microRNAs

In this paper, we present a method for the ultrasensitive detection of microRNAs (miRNAs) utilizing an antibody that specifically recognizes DNA:RNA heteroduplexes, using a silicon photonic microring resonator array transduction platform. Microring resonator arrays are covalently functionalized with...

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Bibliographic Details
Main Authors: Qavi, Abraham J., Kindt, Jared T., Gleeson, Martin A., Bailey, Ryan C.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146633/
https://ncbi.nlm.nih.gov/pubmed/21711056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac201340s
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