Intraclonal Cell Expansion and Selection Driven by B Cell Receptor in Chronic Lymphocytic Leukemia

The mutational status of the immunoglobulin heavy-chain variable region (IGHV) genes utilized by chronic lymphocytic leukemia (CLL) clones defines two disease subgroups. Patients with unmutated IGHV have a more aggressive disease and a worse outcome than patients with cells having somatic IGHV gene...

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Hlavní autoři: Colombo, Monica, Cutrona, Giovanna, Reverberi, Daniele, Fabris, Sonia, Neri, Antonino, Fabbi, Marina, Quintana, Giovanni, Quarta, Giovanni, Ghiotto, Fabio, Fais, Franco, Ferrarini, Manlio
Médium: Artigo
Jazyk:Inglês
Vydáno: ScholarOne 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146619/
https://ncbi.nlm.nih.gov/pubmed/21541442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00047
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