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A Superagonistic Monoclonal Antibody for CD28 Ameliorates Crescentic Glomerulonephritis in Wistar-Kyoto Rats

Regulatory T (Treg) cells play an important role in the resolution of crescentic glomerulonephritis, where a T helper 1 (Th1)-predominant immune response promotes crescent formation. Therefore, agents that increase Treg cells appear to be ideal for suppressing T-cell-mediated renal pathology. We hyp...

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Detalhes bibliográficos
Main Authors: Takabatake, Yoshitsugu, Li, Xiao-Kang, Mizui, Masayuki, Miyasato, Kenro, Matsui, Isao, Kawada, Noritaka, Imai, Enyu, Hünig, Thomas, Takahara, Shiro, Wada, Takashi, Furuichi, Kengo, Rakugi, Hiromi, Isaka, Yoshitaka
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146602/
https://ncbi.nlm.nih.gov/pubmed/21487638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00229
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