Overexpression of Fatty Acid Synthase in Middle Eastern Epithelial Ovarian Carcinoma Activates AKT and Its Inhibition Potentiates Cisplatin-Induced Apoptosis

Fatty acid synthase (FASN), the enzyme responsible for de novo synthesis of fatty acids, has been shown to be deregulated in several cancers, including epithelial ovarian carcinoma (EOC). In this study, we investigated the function of the FASN signaling pathway in a large series of Middle Eastern EO...

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Main Authors: Uddin, Shahab, Jehan, Zeenath, Ahmed, Maqbool, Alyan, Aisha, Al-Dayel, Fouad, Hussain, Azhar, Bavi, Prashant, Al-Kuraya, Khawla S
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146599/
https://ncbi.nlm.nih.gov/pubmed/21442130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00046
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