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Endogenous PTH Deficiency Impairs Fracture Healing and Impedes the Fracture-Healing Efficacy of Exogenous PTH(1-34)

BACKGROUND: Although the capacity of exogenous PTH1-34 to enhance the rate of bone repair is well established in animal models, our understanding of the mechanism(s) whereby PTH induces an anabolic response during skeletal repair remains limited. Furthermore it is unknown whether endogenous PTH is r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ren, Yongxin, Liu, Bo, Feng, Yuxu, Shu, Lei, Cao, Xiaojian, Karaplis, Andrew, Goltzman, David, Miao, Dengshun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146536/
https://ncbi.nlm.nih.gov/pubmed/21829585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023060
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