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Genome-Wide Gene Expression Analysis Suggests an Important Role of Hypoxia in the Pathogenesis of Endemic Osteochondropathy Kashin-Beck Disease

Kashin-Beck Disease (KBD) is an endemic osteochondropathy, the pathogenesis of which remains unclear now. In this study, we compared gene expression profiles of articular cartilage derived respectively from KBD patients and normal controls. Total RNA were isolated, amplified, labeled and hybridized...

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Détails bibliographiques
Auteurs principaux: Zhang, Feng, Guo, Xiong, Wang, Weizhuo, Yan, Hua, Li, Chunyan
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146522/
https://ncbi.nlm.nih.gov/pubmed/21829570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022983
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