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The Role of the p38 MAPK Signaling Pathway in High Glucose-Induced Epithelial-Mesenchymal Transition of Cultured Human Renal Tubular Epithelial Cells

BACKGROUND: Epithelial-mesenchymal transition of tubular epithelial cells, which is characterized by a loss of epithelial cell characteristics and a gain of ECM-producing myofibroblast characteristics, is an essential mechanism that is involved in tubulointerstitial fibrosis, an important component...

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Autors principals: Lv, Zhi-Mei, Wang, Qun, Wan, Qiang, Lin, Jian-Gong, Hu, Meng-Si, Liu, You-Xia, Wang, Rong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146517/
https://ncbi.nlm.nih.gov/pubmed/21829520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022806
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