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Blunting type 1 insulin-like growth factor receptor expression exacerbates neuronal apoptosis following hypoxic/ischemic injury

BACKGROUND: Abundant experimental data have implicated an important role for insulin-like growth factor (IGF) in protecting neuronal cells from injury, including hypoxia/ischemia (H/I) injury, a major cause of neuron death. While the specific interaction of IGFs with neuronal or glial type 1 IGF rec...

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Bibliografische gegevens
Hoofdauteurs: Liu, Wen, D'Ercole, Joseph A, Ye, Ping
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146424/
https://ncbi.nlm.nih.gov/pubmed/21718528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-64
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