Gonadotropin-Releasing Hormone Pulse Sensitivity of Follicle-Stimulating Hormone-β Gene Is Mediated by Differential Expression of Positive Regulatory Activator Protein 1 Factors and Corepressors SKIL and TGIF1

Gonadotropin synthesis and release is dependent on pulsatile stimulation by the hypothalamic neuropeptide GnRH. Generally, slow GnRH pulses promote FSH production, whereas rapid pulses favor LH, but the molecular mechanism underlying this pulse sensitivity is poorly understood. In this study, we dev...

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Detalhes bibliográficos
Main Authors: Mistry, Devendra S., Tsutsumi, Rie, Fernandez, Marina, Sharma, Shweta, Cardenas, Steven A., Lawson, Mark A., Webster, Nicholas J. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146254/
https://ncbi.nlm.nih.gov/pubmed/21659477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-0032
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