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CHF1/Hey2 Promotes Physiological Hypertrophy in Response to Pressure Overload through Selective Repression and Activation of Specific Transcriptional Pathways

We have previously found that CHF1/Hey2 prevents the development of phenylephrine-induced cardiac hypertrophy. To determine the role of CHF1/Hey2 in pressure overload hypertrophy, we performed ascending aortic banding on wild-type and transgenic mice overexpressing CHF1/Hey2 in the myocardium. We fo...

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Autors principals: Yu, Man, Liu, Yonggang, Xiang, Fan, Li, Yuxin, Cullen, Darragh, Liao, Ronglih, Beyer, Richard P., Bammler, Theodor K., Chin, Michael T.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145963/
https://ncbi.nlm.nih.gov/pubmed/20001863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2009.0086
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