Metabotropic glutamate receptors regulate hippocampal CA1 pyramidal neuron excitability via Ca(2+) wave-dependent activation of SK and TRPC channels

ABSTRACT: Group I metabotropic glutamate receptors (mGluRs) play an essential role in cognitive function. Their activation results in a wide array of cellular and molecular responses that are mediated by multiple signalling cascades. In this study, we focused on Group I mGluR activation of IP(3)R-me...

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Hlavní autoři: El-Hassar, Lynda, Hagenston, Anna M, D'Angelo, Lisa Bertetto, Yeckel, Mark F
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2011
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145935/
https://ncbi.nlm.nih.gov/pubmed/21576272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.209783
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