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Inhibition of synaptic transmission and G protein modulation by synthetic Ca(V)2.2 Ca(2+) channel peptides

ABSTRACT: Modulation of presynaptic voltage-dependent Ca(2+) channels is a major means of controlling neurotransmitter release. The Ca(V)2.2 Ca(2+) channel subunit contains several inhibitory interaction sites for Gβγ subunits, including the amino terminal (NT) and I–II loop. The NT and I–II loop ha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bucci, Giovanna, Mochida, Sumiko, Stephens, Gary J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145926/
https://ncbi.nlm.nih.gov/pubmed/21521766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.204735
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