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CCN-2 is up-regulated by and mediates effects of matrix bound advanced glycated end-products in human renal mesangial cells
CCN-2, also known as connective tissue growth factor (CCN-2/CTGF) is a cysteine rich, extracellular matrix protein that acts as a pro-fibrotic cytokine in tissues in many diseases, including in diabetic nephropathy. We have published that soluble advanced glycation end products (AGEs), that are pres...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145870/ https://ncbi.nlm.nih.gov/pubmed/21630131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-011-0137-z |
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