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Nonresonant femtosecond laser vaporization of aqueous protein preserves folded structure
Femtosecond laser vaporization-based mass spectrometry can be used to measure protein conformation in vitro at atmospheric pressure. Cytochrome c and lysozyme are vaporized from the condensed phase into the gas phase intact when exposed to an intense (10(13) W/cm(2)), nonresonant (800 nm), ultrafast...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145716/ https://ncbi.nlm.nih.gov/pubmed/21746908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105673108 |
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