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Nonresonant femtosecond laser vaporization of aqueous protein preserves folded structure

Femtosecond laser vaporization-based mass spectrometry can be used to measure protein conformation in vitro at atmospheric pressure. Cytochrome c and lysozyme are vaporized from the condensed phase into the gas phase intact when exposed to an intense (10(13) W/cm(2)), nonresonant (800 nm), ultrafast...

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Detalhes bibliográficos
Main Authors: Brady, John J., Judge, Elizabeth J., Levis, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145716/
https://ncbi.nlm.nih.gov/pubmed/21746908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105673108
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