Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity

The HDL receptor, scavenger receptor, class B, type I (SR-BI), is a homooligomeric cell surface glycoprotein that controls HDL structure and metabolism by mediating the cellular selective uptake of lipids, mainly cholesteryl esters, from HDL. The mechanism underlying SR-BI-mediated lipid transfer, w...

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Main Authors: Yu, Miao, Romer, Katherine A., Nieland, Thomas J. F., Xu, Shangzhe, Saenz-Vash, Veronica, Penman, Marsha, Yesilaltay, Ayce, Carr, Steven A., Krieger, Monty
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2011
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145699/
https://ncbi.nlm.nih.gov/pubmed/21746906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109078108
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