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A Randomized Controlled Phase Ib Trial of the Malaria Vaccine Candidate GMZ2 in African Children

BACKGROUND: GMZ2 is a fusion protein of Plasmodium falciparum merozoite surface protein 3 (MSP3) and glutamate rich protein (GLURP) that mediates an immune response against the blood stage of the parasite. Two previous phase I clinical trials, one in naïve European adults and one in malaria-exposed...

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Main Authors: Bélard, Sabine, Issifou, Saadou, Hounkpatin, Aurore B., Schaumburg, Frieder, Ngoa, Ulysse Ateba, Esen, Meral, Fendel, Rolf, de Salazar, Pablo Martinez, Mürbeth, Raymund E., Milligan, Paul, Imbault, Nathalie, Imoukhuede, Egeruan Babatunde, Theisen, Michael, Jepsen, Søren, Noor, Ramadhani A., Okech, Brenda, Kremsner, Peter G., Mordmüller, Benjamin
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2011
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145647/
https://ncbi.nlm.nih.gov/pubmed/21829466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022525
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