Stress-Induced PARP Activation Mediates Recruitment of Drosophila Mi-2 to Promote Heat Shock Gene Expression

Eukaryotic cells respond to genomic and environmental stresses, such as DNA damage and heat shock (HS), with the synthesis of poly-[ADP-ribose] (PAR) at specific chromatin regions, such as DNA breaks or HS genes, by PAR polymerases (PARP). Little is known about the role of this modification during c...

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Bibliographic Details
Main Authors: Murawska, Magdalena, Hassler, Markus, Renkawitz-Pohl, Renate, Ladurner, Andreas, Brehm, Alexander
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145624/
https://ncbi.nlm.nih.gov/pubmed/21829383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002206
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