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Gene-Based Tests of Association

Genome-wide association studies (GWAS) are now used routinely to identify SNPs associated with complex human phenotypes. In several cases, multiple variants within a gene contribute independently to disease risk. Here we introduce a novel Gene-Wide Significance (GWiS) test that uses greedy Bayesian...

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Autors principals: Huang, Hailiang, Chanda, Pritam, Alonso, Alvaro, Bader, Joel S., Arking, Dan E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145613/
https://ncbi.nlm.nih.gov/pubmed/21829371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002177
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