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Functional exchangeability of the nuclear localization signal (NLS) of capsid protein between PCV1 and PCV2 in vitro: Implications for the role of NLS in viral replication

BACKGROUND: Porcine circovirus type 2 (PCV2) is believed to be the primary causative agent of postweaning multisystemic wasting syndrome (PMWS). It is supposed that capsid protein of PCV may contribute to replication control via interaction between Cap and Rep in the nucleoplasm. In this study, we d...

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Detalhes bibliográficos
Main Authors: Shuai, Jiangbing, Fu, Linglin, Zhang, Xiaofeng, Zhu, Binglin, Li, XiaoLiang, He, Yongqiang, Fang, Weihuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145596/
https://ncbi.nlm.nih.gov/pubmed/21733152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-341
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