Transgenerational Effects of Di (2-Ethylhexyl) Phthalate in the Male CRL:CD(SD) Rat: Added Value of Assessing Multiple Offspring per Litter

In the rat, some phthalates alter sexual differentiation at relatively low dosage levels by altering fetal Leydig cell development and hormone synthesis, thereby inducing abnormalities of the testis, gubernacular ligaments, epididymis, and other androgen-dependent tissues. In order to define the dos...

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Bibliografiska uppgifter
Huvudupphovsmän: Gray, Leon Earl, Barlow, Norman J., Howdeshell, Kembra L., Ostby, Joseph S., Furr, Johnathan R., Gray, Clark L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2009
Ämnen:
Reproductive and Developmental Toxicology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145405/
https://ncbi.nlm.nih.gov/pubmed/19482887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp109
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