Variations in Apolipoprotein E Frequency With Age in a Pooled Analysis of a Large Group of Older People

Variation in the apolipoprotein E gene (APOE) has been reported to be associated with longevity in humans. The authors assessed the allelic distribution of APOE isoforms ε2, ε3, and ε4 among 10,623 participants from 15 case-control and cohort studies of age-related macular degeneration (AMD) in popu...

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Bibliografiske detaljer
Main Authors: McKay, Gareth J., Silvestri, Giuliana, Chakravarthy, Usha, Dasari, Shilpa, Fritsche, Lars G., Weber, Bernhard H., Keilhauer, Claudia N., Klein, Michael L., Francis, Peter J., Klaver, Caroline C., Vingerling, Johannes R., Ho, Lintje, De Jong, Paulus T. D. V., Dean, Michael, Sawitzke, Julie, Baird, Paul N., Guymer, Robyn H., Stambolian, Dwight, Orlin, Anton, Seddon, Johanna M., Peter, Inga, Wright, Alan F., Hayward, Caroline, Lotery, Andrew J., Ennis, Sarah, Gorin, Michael B., Weeks, Daniel E., Kuo, Chia-Ling, Hingorani, Aroon D., Sofat, Reecha, Cipriani, Valentina, Swaroop, Anand, Othman, Mohammad, Kanda, Atsuhiro, Chen, Wei, Abecasis, Goncalo R., Yates, John R., Webster, Andrew R., Moore, Anthony T., Seland, Johan H., Rahu, Mati, Soubrane, Gisele, Tomazzoli, Laura, Topouzis, Fotis, Vioque, Jesus, Young, Ian S., Fletcher, Astrid E., Patterson, Chris C.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Systematic Reviews and Meta- and Pooled Analyses
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145394/
https://ncbi.nlm.nih.gov/pubmed/21498624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwr015
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