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Studies Toward the Syntheses of Pluramycin Natural Products. The First Total Synthesis of Isokidamycin.

We report the first total synthesis of the complex C-aryl glycoside isokidamycin, the epimer of the naturally-occurring pluramycin antibiotic kidamycin. The synthesis features a highly efficientDiels-Alder reaction between a substituted naphthyne and a glycosylatedfuran to form the anthracene core b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: O'Keefe, B. Michael, Mans, Douglas M., Kaelin, David E., Martin, Stephen F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145363/
https://ncbi.nlm.nih.gov/pubmed/21804649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2011.05.117
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