Membrane Tension, Lipid Adaptation, Conformational Changes, and Energetics in MscL Gating

This study aims to explore gating mechanisms of mechanosensitive channels in terms of membrane tension, membrane adaptation, protein conformation, and energetics. The large conductance mechanosensitive channel from Mycobacterium tuberculosis (Tb-MscL) is used as a model system; Tb-MscL acts as a saf...

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Bibliographic Details
Main Authors: Rui, Huan, Kumar, Ritesh, Im, Wonpil
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2011
Subjects:
Channels and Transporters
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145278/
https://ncbi.nlm.nih.gov/pubmed/21806935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.06.029
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