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A microfluidic-based neurotoxin concentration gradient for the generation of an in vitro model of Parkinson’s disease

In this study, we developed a miniaturized microfluidic-based high-throughput cell toxicity assay to create an in vitro model of Parkinson’s disease (PD). In particular, we generated concentration gradients of 6-hydroxydopamine (6-OHDA) to trigger a process of neuronal apoptosis in pheochromocytoma...

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書誌詳細
主要な著者: Seidi, Azadeh, Kaji, Hirokazu, Annabi, Nasim, Ostrovidov, Serge, Ramalingam, Murugan, Khademhosseini, Ali
フォーマット: Artigo
言語:Inglês
出版事項: American Institute of Physics 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145239/
https://ncbi.nlm.nih.gov/pubmed/21799720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3580756
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