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Endogenous Galanin Protects Mouse Hippocampal Neurons Against Amyloid Toxicity in vitro via Activation of Galanin Receptor-2

Expression of the neuropeptide galanin is known to be upregulated in the brain of patients with Alzheimer’s disease (AD). We and others have shown that galanin plays a neuroprotective role in a number of excitotoxic injury paradigms, mediated by activation of the second galanin receptor subtype (GAL...

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Bibliographic Details
Main Authors: Elliott-Hunt, Caroline R., Holmes, Fiona E., Hartley, Dean M., Perez, Sylvia, Mufson, Elliott J., Wynick, David
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145121/
https://ncbi.nlm.nih.gov/pubmed/21471641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2011-110011
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