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Postexposure Administration of a β(2)-Agonist Decreases Chlorine-Induced Airway Hyperreactivity in Mice

Exposure to chlorine (Cl(2)) damages airway and alveolar epithelia, resulting in acute lung injury and reactive airway dysfunction syndrome. We evaluated the efficacy and mechanisms by which arformoterol, a long-term β(2)-agonist, administered after exposure, mitigated the extent of this injury. Exp...

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Autors principals: Song, Weifeng, Wei, Shipeng, Liu, Gang, Yu, Zhihong, Estell, Kim, Yadav, Amit K., Schwiebert, Lisa M., Matalon, Sadis
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145072/
https://ncbi.nlm.nih.gov/pubmed/20855648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0226OC
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