Sox2 Activates Cell Proliferation and Differentiation in the Respiratory Epithelium

Sox2, a transcription factor critical for the maintenance of embryonic stem cells and induction of pluripotent stem cells, is expressed exclusively in the conducting airway epithelium of the lung, where it is required for differentiation of nonciliated, goblet, and ciliated cells. To determine the r...

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Hlavní autoři: Tompkins, David H., Besnard, Valérie, Lange, Alexander W., Keiser, Angela R., Wert, Susan E., Bruno, Michael D., Whitsett, Jeffrey A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145063/
https://ncbi.nlm.nih.gov/pubmed/20855650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0149OC
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