Focal Adhesion Kinase Silencing Augments Docetaxel-Mediated Apoptosis in Ovarian Cancer Cells

OBJECTIVE: Docetaxel causes cell death through induction of apoptosis; however, cell death characteristics for docetaxel have not yet been fully elucidated. We examined the role of focal adhesion kinase (FAK) cleavage in docetaxel-mediated apoptosis. METHODS: FAK degradation after treatment with doc...

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Main Authors: Halder, Jyotsnabaran, Landen, Charles N., Lutgendorf, Susan K., Li, Yang, Jennings, Nicholas B., Fan, Dominic, Nelkin, Gina M., Schmandt, Rosemarie, Schaller, Michael D., Sood, Anil K.
Format: Artigo
Jezik:Inglês
Izdano: 2005
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144933/
https://ncbi.nlm.nih.gov/pubmed/16361572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-05-1728
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