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Adenovirus-Vectored Drug-Vaccine Duo as a Rapid-Response Tool for Conferring Seamless Protection against Influenza

Few other diseases exert such a huge toll of suffering as influenza. We report here that intranasal (i.n.) administration of E1/E3-defective (ΔE1E3) adenovirus serotype 5 (Ad5) particles rapidly induced an anti-influenza state as a means of prophylactic therapy which persisted for several weeks in m...

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Autors principals: Zhang, Jianfeng, Tarbet, E. Bart, Feng, Tsungwei, Shi, Zhongkai, Van Kampen, Kent R., Tang, De-chu C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144911/
https://ncbi.nlm.nih.gov/pubmed/21818346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022605
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