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Overexpression, crystallization, and preliminary X-ray crystallographic analysis of shikimate dehydrogenase from Thermotoga maritima

Shikimate dehydrogenase (SDH), which catalyses the NADPH-dependent reduction of 3-dehydroshikimate to shikimate in the shikimate pathway, is an attractive target for the development of herbicides and antimicrobial agents. Previous structural studies showed that SDH exists in two conformations, an op...

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Dettagli Bibliografici
Autore principale: Lee, Hyung Ho
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144806/
https://ncbi.nlm.nih.gov/pubmed/21795804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111019877
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