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[F-18]FDDNP microPET imaging correlates with brain Aβ burden in a transgenic rat model of Alzheimer disease: Effects of aging, in vivo blockade, and anti-Aβ antibody treatment

In vivo detection of Alzheimer's disease (AD) neuropathology in living patients using positron emission tomography (PET) in conjunction with high affinity molecular imaging probes for β-amyloid (Aβ) and tau has the potential to assist with early diagnosis, evaluation of disease progression, and...

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Detalhes bibliográficos
Main Authors: Teng, Edmond, Kepe, Vladimir, Frautschy, Sally A., Liu, Jie, Satyamurthy, Nagichettiar, Yang, Fusheng, Chen, Ping-Ping, Cole, Graham B., Jones, Mychica R., Huang, Sung-Cheng, Flood, Dorothy G., Trusko, Stephen P., Small, Gary W., Cole, Gregory M., Barrio, Jorge R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144750/
https://ncbi.nlm.nih.gov/pubmed/21605674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.05.003
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