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High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine

Phosphatidylserine (PS) plays a central role in cell signaling and in the biosynthesis of other lipids. To date, however, the subcellular distribution and transmembrane topology of this crucial phospholipid remain ill-defined. We transfected cells with a GFP-tagged C2 domain of lactadherin to detect...

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Autors principals: Fairn, Gregory D., Schieber, Nicole L., Ariotti, Nicholas, Murphy, Samantha, Kuerschner, Lars, Webb, Richard I., Grinstein, Sergio, Parton, Robert G.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144401/
https://ncbi.nlm.nih.gov/pubmed/21788369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201012028
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