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Reduced Memory CD4(+) T-Cell Generation in the Circulation of Young Children May Contribute to the Otitis-Prone Condition

Background. An explanation for the immunologic dysfunction that causes children to be prone to repeated episodes of acute otitis media (AOM) has long been sought. Poor antibody response has been associated with the otitis-prone condition; however, there is no precise mechanistic explanation for this...

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Main Authors: Sharma, Sharad K., Casey, Janet R., Pichichero, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144174/
https://ncbi.nlm.nih.gov/pubmed/21791667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir340
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