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The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor

BACKGROUND: Loss of heterozygosity at 18q, which includes the Deleted in Colorectal Cancer (DCC) gene, has been linked to many human cancers. However, it is unclear if loss of DCC is the specific underlying cause of these cancers. The Drosophila imaginal discs are excellent systems in which to study...

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Main Authors: VanZomeren-Dohm, Adrienne, Sarro, Joseph, Flannery, Ellen, Duman-Scheel, Molly
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144007/
https://ncbi.nlm.nih.gov/pubmed/21672235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-11-41
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