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Bi-Directional Effect of Increasing Doses of Baclofen on Reinforcement Learning

In rodents as well as in humans, efficient reinforcement learning depends on dopamine (DA) released from ventral tegmental area (VTA) neurons. It has been shown that in brain slices of mice, GABA(B)-receptor agonists at low concentrations increase the firing frequency of VTA–DA neurons, while high c...

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Detalhes bibliográficos
Main Authors: Terrier, Jean, Ort, Andres, Yvon, Cédric, Saj, Arnaud, Vuilleumier, Patrik, Lüscher, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143686/
https://ncbi.nlm.nih.gov/pubmed/21811448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2011.00040
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