Notch and Ras promote sequential steps of excretory tube development in C. elegans

Receptor tyrosine kinases and Notch are crucial for tube formation and branching morphogenesis in many systems, but the specific cellular processes that require signaling are poorly understood. Here we describe sequential roles for Notch and Epidermal growth factor (EGF)-Ras-ERK signaling in the dev...

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Detalhes bibliográficos
Main Authors: Abdus-Saboor, Ishmail, Mancuso, Vincent P., Murray, John I., Palozola, Katherine, Norris, Carolyn, Hall, David H., Howell, Kelly, Huang, Kai, Sundaram, Meera V.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143567/
https://ncbi.nlm.nih.gov/pubmed/21771815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.068148
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