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Notch and Ras promote sequential steps of excretory tube development in C. elegans

Receptor tyrosine kinases and Notch are crucial for tube formation and branching morphogenesis in many systems, but the specific cellular processes that require signaling are poorly understood. Here we describe sequential roles for Notch and Epidermal growth factor (EGF)-Ras-ERK signaling in the dev...

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Détails bibliographiques
Auteurs principaux: Abdus-Saboor, Ishmail, Mancuso, Vincent P., Murray, John I., Palozola, Katherine, Norris, Carolyn, Hall, David H., Howell, Kelly, Huang, Kai, Sundaram, Meera V.
Format: Artigo
Langue:Inglês
Publié: Company of Biologists 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143567/
https://ncbi.nlm.nih.gov/pubmed/21771815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.068148
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