The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion

Natural models of heart regeneration in lower vertebrates such as zebrafish are based on invasive surgeries causing mechanical injuries that are limited in size. Here, we created a genetic cell ablation model in zebrafish that facilitates inducible destruction of a high percentage of cardiomyocytes....

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Main Authors: Wang, Jinhu, Panáková, Daniela, Kikuchi, Kazu, Holdway, Jennifer E., Gemberling, Matthew, Burris, James S., Singh, Sumeet Pal, Dickson, Amy L., Lin, Yi-Fan, Sabeh, M. Khaled, Werdich, Andreas A., Yelon, Deborah, MacRae, Calum A., Poss, Kenneth D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Company of Biologists 2011
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143562/
https://ncbi.nlm.nih.gov/pubmed/21752928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.068601
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