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Neuroprotective Interventions Targeting Detrimental Host Immune Responses Protect Mice From Fatal Alphavirus Encephalitis
Systemic treatment with the tetracycline derivative, minocycline, attenuates neurological deficits in animal models of amyotrophic lateral sclerosis, hypoxic-ischemic brain injury, and multiple sclerosis. Inhibition of microglial activation within the CNS is one mechanism proposed to underlie the dr...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3143496/ https://ncbi.nlm.nih.gov/pubmed/17549013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.jnen.0000263867.46070.e2 |
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