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Host Defense Pathways: role of redundancy and compensation in infectious disease phenotypes

Innate host defense pathways consist of microbial sensors, their signaling pathways and the anti-microbial effector mechanisms. Several classes of host defense pathways are currently known, each comprising several pattern-recognition receptors that detect different types of pathogens. These pathways...

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Detalhes bibliográficos
Main Authors: Nish, Simone, Medzhitov, Ruslan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143490/
https://ncbi.nlm.nih.gov/pubmed/21616433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.05.009
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