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Edg-1, the G protein–coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

Sphingolipid signaling pathways have been implicated in many critical cellular events. Sphingosine-1-phosphate (SPP), a sphingolipid metabolite found in high concentrations in platelets and blood, stimulates members of the endothelial differentiation gene (Edg) family of G protein–coupled receptors...

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Published in:J Clin Invest
Main Authors: Liu, Yujing, Wada, Ryuichi, Yamashita, Tadashi, Mi, Yide, Deng, Chu-Xia, Hobson, John P., Rosenfeldt, Hans M., Nava, Victor E., Chae, Sung-Suk, Lee, Menq-Jer, Liu, Catherine H., Hla, Timothy, Spiegel, Sarah, Proia, Richard L.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2000
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314347/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11032855/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI10905
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