Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture

Background. Chronic hepatitis C virus (HCV)–induced liver fibrosis involves upregulation of transforming growth factor (TGF)–β and subsequent hepatic stellate cell (HSC) activation. MicroRNAs (miRNAs) regulate HCV infection and HSC activation. Methods. TaqMan miRNA profiling identified 12 miRNA fami...

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Autors principals: Bandyopadhyay, Sarmistha, Friedman, Robin C., Marquez, Rebecca T., Keck, Kathy, Kong, Benjamin, Icardi, Michael S., Brown, Kyle E., Burge, Christopher B., Schmidt, Warren N., Wang, Yulei, McCaffrey, Anton P.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143452/
https://ncbi.nlm.nih.gov/pubmed/21606534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir186
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