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Molecular Targeted Approaches in Mantle Cell lymphoma.
Mantle cell lymphoma (MCL) is a malignancy of mature B cells characterized by the translocation t(11;14) that leads to aberrant expression of cyclin D1. Response to first-line chemotherapy is good but most patients relapse resulting in a median survival of 5-7 years. The important PI3K/AKT/mTOR path...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3143377/ https://ncbi.nlm.nih.gov/pubmed/21782064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2011.05.001 |
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