Plasma Klotho and Mortality Risk in Older Community-Dwelling Adults

BACKGROUND. The aging-suppressor gene klotho encodes a single-pass transmembrane protein that in mice is known to extend life span when overexpressed and resemble accelerated aging when expression is disrupted. It is not known whether there is a relationship between plasma levels of secreted klotho...

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Main Authors: Semba, Richard D., Cappola, Anne R., Sun, Kai, Bandinelli, Stefania, Dalal, Mansi, Crasto, Candace, Guralnik, Jack M., Ferrucci, Luigi
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Journal of Gerontology: MEDICAL SCIENCES
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143348/
https://ncbi.nlm.nih.gov/pubmed/21474560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glr058
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