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Signaling by the Phosphatase MKP-1 in Dendritic Cells Imprints Distinct Effector and Regulatory T Cell Fates
Naïve T cells respond to antigens by differentiating into effector and regulatory lineages. Whereas the roles of T cell intrinsic pathways have been extensively studied, how T cell lineage choices are controlled by innate immune signals remains elusive. Here we report that dendritic cell (DC)-expres...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3142929/ https://ncbi.nlm.nih.gov/pubmed/21723158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.05.014 |
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