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Signaling by the Phosphatase MKP-1 in Dendritic Cells Imprints Distinct Effector and Regulatory T Cell Fates

Naïve T cells respond to antigens by differentiating into effector and regulatory lineages. Whereas the roles of T cell intrinsic pathways have been extensively studied, how T cell lineage choices are controlled by innate immune signals remains elusive. Here we report that dendritic cell (DC)-expres...

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Autors principals: Huang, Gonghua, Wang, Yanyan, Shi, Lewis Z., Kanneganti, Thirumala-Devi, Chi, Hongbo
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142929/
https://ncbi.nlm.nih.gov/pubmed/21723158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.05.014
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