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Translocation of a Vibrio cholerae Type VI Secretion Effector Requires Bacterial Endocytosis by Host Cells

The type VI secretion system (T6SS) is a virulence mechanism common to several Gram-negative pathogens. In Vibrio cholerae, VgrG-1 is required for T6SS-dependent secretion. VgrG-1 is also secreted by T6SS and displays a C-terminal actin cross-linking domain (ACD). Using a heterologous reporter enzym...

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Detalhes bibliográficos
Main Authors: Ma, Amy T., McAuley, Steven, Pukatzki, Stefan, Mekalanos, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142922/
https://ncbi.nlm.nih.gov/pubmed/19286133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2009.02.005
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