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Elevated Rates of Protein Secretion, Evolution, and Disease Among Tissue-Specific Genes

Variation in gene expression has been held responsible for the functional and morphological specialization of tissues. The tissue specificity of genes is known to correlate positively with gene evolution rates. We show here, using large data sets, that when a gene is expressed highly in a small numb...

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Detalhes bibliográficos
Main Authors: Winter, Eitan E., Goodstadt, Leo, Ponting, Chris P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC314278/
https://ncbi.nlm.nih.gov/pubmed/14707169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1924004
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