Metformin as an energy restriction mimetic agent for breast cancer prevention

BACKGROUND: This study examined whether metformin administration inhibited chemically induced mammary carcinogenesis in rats. In cancer prevention, metformin may act (1) indirectly through reducing systemic risk factors; or (2) directly through AMPK-mediated signaling. To begin to delineate clinical...

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Bibliographische Detailangaben
Hauptverfasser: Zhu, Zongjian, Jiang, Weiqin, Thompson, Matthew D., McGinley, John N., Thompson, Henry J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications 2011
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142764/
https://ncbi.nlm.nih.gov/pubmed/21799661
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