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Treatment of Streptozotocin-Induced Diabetic Rats with Alogliptin: Effect on Vascular and Neural Complications

We sought to determine the effect of dipeptidyl peptidase IV (DPP-IV) inhibition on streptozotocin diabetes-induced vascular and neural dysfunction. After 4 weeks of untreated diabetes, rats were treated for 12 weeks with Alogliptin (DPP-IV inhibitor). Diabetes caused a slowing of motor and sensory...

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Autors principals: Davidson, Eric P., Coppey, Lawrence J., Dake, Brian, Yorek, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142682/
https://ncbi.nlm.nih.gov/pubmed/21822422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/810469
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