Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck

BACKGROUND: Phospholipase C epsilon 1 (PLCE1) (an effector of Ras) belonging to the phospholipase family plays crucial roles in carcinogenesis and progression of several cancers, including squamous cell carcinoma of the head and neck (SCCHN). A single nucleotide polymorphism (SNP, rs2274223) in PLCE...

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Hlavní autoři: Ma, Hongxia, Wang, Li-E, Liu, Zhensheng, Sturgis, Erich M, Wei, Qingyi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142535/
https://ncbi.nlm.nih.gov/pubmed/21689432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-258
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